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Spravato

A New Path Forward for Treatment Resistant Depression

Please check with your insurance provider to confirm your coverage and out-of-pocket costs for this medication. 

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If you've tried multiple antidepressants and still struggle with depression, you're not alone. About 1 in 3 people with depression don't find relief from traditional oral medications. That's where Spravato®  comes in, a breakthrough treatment designed for adults with treatment-resistant depression (TRD).

What is Spravato?

Spravato is the only FDA-approved nasal spray for TRD. It works differently than traditional antidepressants by targeting glutamate, a chemical messenger in the brain linked to mood regulation. Spravato is used alongside an oral antidepressant and is administered under medical supervision in a certified healthcare setting. 

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What to Expect with Spravato

  • Rapid Relief: Many patients report improvement in symptoms within 24 hours to 4 weeks

  • Monitored Care: You'll be observed for at least 2 hours after each dose to ensure safety with this medication. 

  • Supportive Environment: Our pharmacy partners with certified clinics to ensure you receive compassionate and professional care. 

Safety and Side Effects

Spravato may cause: 

  • Dizziness or sedation 

  • Feeling disconnected from reality (dissociation) 

  • Increased blood pressure 

  • Nausea or vomiting 

Because of these effects, Spravato is only available through a Risk Evaluation and Mitigation Strategy (REMS) program. Your provider will guide you through every step. Contact us if you'd like more information on Spravato or finding a provider. 

If you or a loved one are experiencing suicidal thoughts, please seek help immediately. Spravato is not a substitute for emergency care. 

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